Gry I. Skodje, MSc, RD
Department of Clinical Nutrition
Division of Cancer Medicine
Oslo University Hospital, Norway
Title: Fructan, Rather Then Gluten, Induces Symptoms In Patients with Self-Reported Non-Celiac Gluten Sensitivity. Skodje GI, Sarna VK, Minelle IH, Rolfsen KL, Muir JG, Gibson PR, Veier.d MB, Henriksen C, Lundin KEA. Gastroenterology 2018 Feb;154 (3):529-539. doi: 10.1053/j.gastro.2017.10.040. Epub 2017 Nov 2.
Non-celiac gluten sensitivity is characterized by symptom improvement after gluten withdrawal in absence of celiac disease. The mechanisms of non-celiac gluten sensitivity are unclear, and there are no biomarkers for this disorder. This article outlined the study aimed to investigate the effect of gluten and fructans separately in individuals with self-reported gluten sensitivity. This article concluded that in a randomized, doubleblind, placebo-controlled crossover study of individuals with self-reported non-celiac gluten sensitivity, fructans were found to induce symptoms, measured by the GSRS-IBS.