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The diagnosis and management of IBS varies greatly within primary care, reflecting the large variation in how IBS is perceived. The awareness and use of diagnostic criteria is low based on current literature, and PCP diagnosis appears to be based mainly on exclusion, even if an early tentative diagnosis is often established. However, recent trends in diagnostic strategies may not yet be fully captured in the published literature. A positive clinical diagnosis can be strongly encouraged since recent evidence suggests it is less costly and non-inferior to in terms of patient outcomes and excluding organic disease. The specific goal of the working team was to provide a comprehensive overview of functional GI disease in primary care, with clear recommendations for daily practice, under reference to the body of knowledge in the Rome report.


Irritable Bowel Syndrome: An Integrated Explanatory Model for Clinical Practice
Hungin, A. P., Becher, A., Cayley, B., Heidelbaugh, J. J., Muris, J. W.,
Rubin, G., Seifert, A., Russell, N. De Wit, N. J.
(2015). Neurogastroenterol Motil, 27(6), 750-763

Systematic Review: The Perceptions, Diagnosis and Management of Irritable Bowel Syndrome
in Primary Care – A Rome Foundation Working Team Report

Hungin, A. P. S., Molloy-Bland, M., Claes, R., Heidelbaugh, J.,
Cayley Jr, W. E., Muris, J., Rubin, G., Seifert, A., de Wit, N.
(2014). Alimentary Pharmacology & Therapeutics, 40(10), 1133-1145.

Members of the Working Team


A. Pali Hungin, MD
School of Medicine, Pharmacy and Health
Durham University
Stockton-on-Tees, UK


Joel Heidelbaugh, MD
Departments of Family Medicine and Urology
Medical School, University of Michigan
Ann Arbor, MI, USA

Anja Becher, PhD
School of Medicine, Pharmacy and Health
Durham University
Stockton-on-Tees, UK
Research and Evaluation Unit
Oxford PharmaGenesis Ltd
Oxford, UK

William Cayley, MD
Department of Family Medicine
University of Wisconsin
Madison, WI, USA

Richard Claes, PhD
Research Evaluation Unit
Oxford PharmaGenesisTMLtd
Oxford, UK

Niek J De Wit, MD, PhD
Julius Center for Health Sciences and Primary Care
University Medical Center Utrecht
Utrecht, The Netherlands

Michael Molloy-Bland, MD
School of Medicine, Pharmacy and Health
Durham University, Stockton-on-Tees, UK

Research Evaluation Unit,
Oxford PharmaGenesis Ltd
Oxford, UK

Jean Muris, PhD
Department of Family Medicine
Care and Public Health Research Institute (CAPHRI)
Maastricht University
Maastricht, The Netherlands

Greg Rubin, MD
School of Medicine, Pharmacy and Health
Durham University
Stockton-on-Tees, UK

Andrew Russell, PhD
Department of Anthropology
Durham University
Durham, UK

Bohumil Seifert, PhD
Institute of General Practice
Charles University
Praha, Czech Republic

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