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About

There is consistent evidence indicating that functional dyspepsia (FD) and irritable bowel syndrome (IBS) can develop following an episode of acute infectious gastroenteritis, with an overall OR of 2.5 for the presence of a FGID at six months post-infection compared to controls. This Working Team reviewed the existing literature on the role of infections in functional GI disorders, focusing on clinical and translational aspects. This included epidemiological issues, risk factors, the role of microbiota and the immune system, the relevance of animal models, diagnosis, prognosis, and management. Based on our literature search, we provided recommendations on implementing current knowledge into clinical practice in order to improve the health of our patients, as well as recommendations for future areas of research. These recommendations are summarized in the following journal article, appearing in Gastroenterology.

Publication

Rome Foundation Working Team Report on Post-Infection Irritable Bowel Syndrome
Barbara, G., Grover, M., Bercik, P., Corsetti, M., Ghoshal, U. C., Ohman, L., & Rajilić-Stojanović, M.
Gastroenterology, 156(1), 46-58.e47
Abstract

Members of the Working Team

Chair

Giovanni  Barbara, MD
Department of Medical and Surgical Sciences
University of Bologna
Bologna, Italy

Co-Chair

Madhusudan Grover, MBBS
Enteric NeuroScience Program, Division of Gastroenterology and Hepatology
Mayo Clinic
Rochester, Minnesota

Premysl  Bercik, MD
Department of Medicine, Farncombe Family Digestive Health Research Institute
McMaster University
Hamilton, Ontario, Canada

Mirjana Rajilić-Stojanović, PhD
Department of Biochemical Engineering and Biotechnology, Faculty of Technology and Metallurgy
University of Belgrade
Belgrade, Serbia

Maura Corsetti, PhD
Nottingham Digestive Diseases Biomedical Research Centre
National Institute for Health Research
Nottingham University Hospitals NHS Trust
University of Nottingham
Nottingham, United Kingdom

Lena Ohman, MD, PhD
Department of Microbiology and Immunology
Sahlgrenska Academy, University of Gothenburg
Gothenburg, Sweden

Uday C. Ghoshal, MD
Department of Gastroenterology
Sanjay Gandhi Post Graduate Institute of Medical Sciences
Lucknow, India

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