Professor of Medicine
G Oppenheimer Center for Neurobiology of Stress and Resilience
Goodman-Luskin Microbiome Center
Walter and Shirley Wang Center for Integrative Digestive Health
Vatche and Tamar Manoukian Division of Digestive Diseases
David Geffen School of Medicine at University of California, Los Angeles Los Angeles, CA, USA
Lin Chang, MD, is a Professor of Medicine and Vice-Chief of the Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine at the David Geffen School of Medicine at UCLA. She serves as the Co-Director of the G Oppenheimer Center for Neurobiology of Stress and Resilience (CNSR), Director of the Walter and Shirley Wang Center for Integrative Digestive Health, and Director of the Clinical Studies and Database Core of the Goodman-Luskin Microbiome Center (GLMC) at the David Geffen School of Medicine at UCLA. The CNSR and GLMC are integrated centers that are interdisciplinary research and education organizations, dedicated to the study of brain-body interactions and the microbiome in health and disease. She is also Program Director of the UCLA Gastroenterology Fellowship Program. The Wang Center for Integrative Digestive Health is an interdisciplinary clinical and research program for patients with digestive disorders. Dr. Chang’s clinical expertise is in disorders of gut-brain interaction (DGBI), specifically irritable bowel syndrome (IBS), chronic constipation and chronic abdominal pain. Her research focuses on brain-gut interactions underlying IBS and is funded by the NIH, foundation, industry, and philanthropy. Specifically, her research studies the pathophysiology of IBS related to stress, early-life adversity, sex differences, genetic and epigenetic factors, the gut microbiome, and IBS treatment.
Dr. Chang is the recipient of the Janssen Award in Gastroenterology for Basic or Clinical Research, the AGA Distinguished Clinician Award, AGA Distinguished Educator Award, AGA Neurogastroenterology Section Research Mentor Award. She is the Past-President of the American Neurogastroenterology and Motility Society (ANMS). She serves on the Rome V Editorial Board as well as the liaison for three Rome IV committees: 1) Bowel Disorders, 2) Patient experience, Gender, Age, and Social Determinants of Health; and 3) Treatment Trials committees. Dr. Chang is a fellow of the American Gastroenterological Association and American College of Gastroenterology. She serves as Associate Editor of Gastroenterology. Dr. Chang is a member of the FDA Gl Drug Advisory Committee. She has authored more than 200 original research articles, 75 review articles, and 30 book chapters on her specialty interests.
