About
The Rome Foundation Working Team on Pharmacological Trials in Children with IBS was formed because, despite chronic abdominal pain being one of the symptoms most commonly encountered by pediatric providers and gastroenterologists, there is little published evidence of efficacy for the most commonly used treatments. Thus, there was an urgent need to conduct clinical trials on existing and novel therapies. This working team developed guidelines for the design of clinical trials in children with IBS based on evidence from published data and consensus of expert opinion.
Publications
Recommendations for Pharmacological Clinical Trials in Children with Irritable Bowel Syndrome: the Rome Foundation Pediatric Subcommittee on Clinical Trials
Saps, M., van Tilburg, M. A. L., Lavigne, J. V., Miranda, A., Benninga, M. A., Taminiau, J. A., & Di Lorenzo, C.
(2016). Neurogastroenterology and Motility, 28(11), 1619-1631
Abstract
Members of the Working Team
Chair
Miguel Saps, MD
Division of Pediatric Gastroenterology, Hepatology & Nutrition
Nationwide Children’s Hospital
Columbus, OH, USA
Marc Benninga, MD
Department of Pediatric Gastroenterology and Nutrition
Emma Children’s Hospital/Academic Medical Center
Amsterdam, The Netherlands
Carlo Di Lorenzo, MD
Division of Pediatric Gastroenterology, Hepatology & Nutrition
Nationwide Children’s Hospital
Columbus, Ohio, USA
John Lavigne, PhD
Department of Child and Adolescent Psychiatry
Ann & Robert H. Lurie Children’s Hospital of Chicago
Chicago, Illinois, USA
Feinberg School of Medicine
Northwestern University
Chicago, Illinois, USA
Mary Ann and J. Milburn Smith Child Health Research Program
Chicago, Illinois, USA
Adrian Miranda, MD
Division of Pediatric Gastroenterology Hepatology & Nutrition
Medical College of Wisconsin
Milwaukee, Wisconsin, USA
Miranda van Tilburg, PhD
Division of Gastroenterology and Hepatology, Center for Functional Gastrointestinal and Motility Disorders
University of North Carolina
Chapel Hill, North Carolina, USA
Johannes Taminiau, MD
Member of the Pediatric Committee (PDCO)
European Medicines Agency
London, UK