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Post-infection IBS Working Team

Rationale and Objectives
There is consistent evidence indicating that functional dyspepsia (FD) and irritable bowel syndrome (IBS) can develop following an episode of acute infectious gastroenteritis, with an overall OR of 2.5 for the presence of a FGID at six months post-infection compared to controls.

Several new data have been published in the last 10 years on post-infectious functional GI disorders, particularly detailing the epidemiology, risk factors, pathophysiology and the involvement of the microbiota.

Specific aims of the Working Team

  • To critically review the existing literature on the role of infections in functional GI disorders, with focus on clinical and translational aspects. This will include epidemiological issues, risk factors, the role of microbiota and the immune system, the relevance of animal models, diagnosis, prognosis, and management.
  • Based on the literature search, provide recommendations how to implement the current knowledge into clinical practice, in order to improve the health of our patients.
  • Give recommendations for future work in order to improve the current knowledge on post-infectious functional GI disorders.
  • These goals will be summarized in an extensive, but clinically useful, review, submitted to one of the major scientific journals in our field.

Members of the Working Team:
The selection consist of individuals with research and/or clinical expertise in the area of interest. Factors considered in selection include international recognition, a record of scientific publication, ability to work in a group to achieve consensus, and geographical diversity.

Giovanni Barbara, MD – Chair

Madhusudan Grover, MD – Co-Chair

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