About
There is consistent evidence indicating that functional dyspepsia (FD) and irritable bowel syndrome (IBS) can develop following an episode of acute infectious gastroenteritis, with an overall OR of 2.5 for the presence of a FGID at six months post-infection compared to controls. This Working Team reviewed the existing literature on the role of infections in functional GI disorders, focusing on clinical and translational aspects. This included epidemiological issues, risk factors, the role of microbiota and the immune system, the relevance of animal models, diagnosis, prognosis, and management. Based on our literature search, we provided recommendations on implementing current knowledge into clinical practice in order to improve the health of our patients, as well as recommendations for future areas of research. These recommendations are summarized in the following journal article, appearing in Gastroenterology.
Publication
Rome Foundation Working Team Report on Post-Infection Irritable Bowel Syndrome
Barbara, G., Grover, M., Bercik, P., Corsetti, M., Ghoshal, U. C., Ohman, L., & Rajilić-Stojanović, M.
(2019). Gastroenterology, 156(1), 46-58.e47
Abstract
Members of the Working Team
Chair
Giovanni Barbara, MD
Department of Medical and Surgical Sciences
University of Bologna
Bologna, Italy
Co-Chair
Madhusudan Grover, MBBS
Enteric NeuroScience Program, Division of Gastroenterology and Hepatology
Mayo Clinic
Rochester, Minnesota
Premysl Bercik, MD
Department of Medicine, Farncombe Family Digestive Health Research Institute
McMaster University
Hamilton, Ontario, Canada
Mirjana Rajilić-Stojanović, PhD
Department of Biochemical Engineering and Biotechnology, Faculty of Technology and Metallurgy
University of Belgrade
Belgrade, Serbia
Maura Corsetti, PhD
Nottingham Digestive Diseases Biomedical Research Centre
National Institute for Health Research
Nottingham University Hospitals NHS Trust
University of Nottingham
Nottingham, United Kingdom
Lena Ohman, MD, PhD
Department of Microbiology and Immunology
Sahlgrenska Academy, University of Gothenburg
Gothenburg, Sweden
Uday C. Ghoshal, MD
Department of Gastroenterology
Sanjay Gandhi Post Graduate Institute of Medical Sciences
Lucknow, India