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Meet the Experts with Sarah Kinsinger, PhD

Brain-Gut Behavioral Therapies with Sarah Kinsinger, PhD

How can treatments that target the brain help manage digestive symptoms? In this installment of the Rome Foundation’s Meet the Experts series, Sarah Kinsinger, PhD, explains the science behind brain-gut behavioral therapies and their role in caring for people with disorders of gut-brain interaction (DGBIs), including irritable bowel syndrome (IBS) and functional dyspepsia.

Dr. Kinsinger is a clinical health psychologist and professor of medicine in the Division of Gastroenterology and Nutrition at Loyola University Medical Center. She chairs the Rome Foundation’s GastroPsych section and served as co-chair of the Non-Pharmacological Support Committee for the Rome V process.

Beginning at 0:48, Dr. Kinsinger explores the two-way communication between the brain and digestive system, explaining why treatments that target brain-gut pathways can help manage digestive symptoms. She introduces brain-gut behavioral therapies and describes how these specialized approaches differ from general counseling.

For a closer look at cognitive behavioral therapy (CBT), skip to 2:06. Dr. Kinsinger explains how CBT can help people manage symptom-related worry, practice skills such as diaphragmatic breathing, and return to meaningful activities they may have been avoiding. At 2:50, she introduces gut-directed hypnotherapy, describing how focused attention, deep relaxation, and therapeutic suggestions can influence digestive functioning and the way the brain processes signals from the gut.

At 4:48, Dr. Kinsinger explains the vicious cycle of digestive symptoms, stress, worry, and heightened attention to bodily sensations, and how these responses can intensify symptoms. For ways to interrupt that cycle, skip to 6:12. She describes how brain-gut behavioral therapies can address GI-specific stress and help people regain a sense of control. This approach recognizes that symptoms are real and that addressing both the brain and gut can be an important part of care.

Watch to better understand how brain-gut behavioral therapies can help interrupt this cycle, support symptom management, and improve quality of life.